The Anticancer Drug AUY922 Generates a Proteomics Fingerprint That Is Highly Conserved among Structurally Diverse Hsp90 Inhibitors | Journal of Proteome Research
Sponsor Novartis Generic Drug Name Alpelisib/BYL719 and AUY922 Trial Indication(s) Advanced or metastatic gastric cancer (GC) ca
![The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth. - Abstract - Europe PMC The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth. - Abstract - Europe PMC](https://europepmc.org/articles/PMC3681857/bin/nihms457583f1.jpg)
The HSP90 inhibitor NVP-AUY922 potently inhibits non-small cell lung cancer growth. - Abstract - Europe PMC
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NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models | Breast Cancer Research | Full Text
HSP90 Inhibitor, NVP-AUY922, Improves Myelination in Vitro and Supports the Maintenance of Myelinated Axons in Neuropathic Mice | ACS Chemical Neuroscience
![Exploring the inhibitory mechanism of resorcinylic isoxazole amine NVP- AUY922 towards the discovery of potential heat shock protein 90 (Hsp90) inhibitors - ScienceDirect Exploring the inhibitory mechanism of resorcinylic isoxazole amine NVP- AUY922 towards the discovery of potential heat shock protein 90 (Hsp90) inhibitors - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S2468227622000163-gr3.jpg)
Exploring the inhibitory mechanism of resorcinylic isoxazole amine NVP- AUY922 towards the discovery of potential heat shock protein 90 (Hsp90) inhibitors - ScienceDirect
![NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis | Cell Death Discovery NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis | Cell Death Discovery](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41420-022-00887-9/MediaObjects/41420_2022_887_Fig2_HTML.png)
NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis | Cell Death Discovery
![Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells | Anticancer Research Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells | Anticancer Research](https://ar.iiarjournals.org/content/anticanres/40/11/6137/F4.large.jpg)
Heat Shock Protein 90 Inhibitors AUY922, BIIB021 and SNX5422 Induce Bim-mediated Death of Thyroid Carcinoma Cells | Anticancer Research
![Targeting HSP90 by the Novel Inhibitor NVP-AUY922 Reduces Growth and Angiogenesis of Pancreatic Cancer | Anticancer Research Targeting HSP90 by the Novel Inhibitor NVP-AUY922 Reduces Growth and Angiogenesis of Pancreatic Cancer | Anticancer Research](https://ar.iiarjournals.org/content/anticanres/32/7/2551/F2.large.jpg)
Targeting HSP90 by the Novel Inhibitor NVP-AUY922 Reduces Growth and Angiogenesis of Pancreatic Cancer | Anticancer Research
![Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer - ScienceDirect Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer - ScienceDirect](https://ars.els-cdn.com/content/image/1-s2.0-S0169500211004806-gr1.jpg)
Strong anti-tumor effect of NVP-AUY922, a novel Hsp90 inhibitor, on non-small cell lung cancer - ScienceDirect
![Frontiers | Complex Crystal Structure Determination of Hsp90N-NVP-AUY922 and In Vitro Anti-NSCLC Activity of NVP-AUY922 Frontiers | Complex Crystal Structure Determination of Hsp90N-NVP-AUY922 and In Vitro Anti-NSCLC Activity of NVP-AUY922](https://www.frontiersin.org/files/Articles/847556/fonc-12-847556-HTML/image_m/fonc-12-847556-g004.jpg)
Frontiers | Complex Crystal Structure Determination of Hsp90N-NVP-AUY922 and In Vitro Anti-NSCLC Activity of NVP-AUY922
![NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis | Cell Death Discovery NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis | Cell Death Discovery](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fs41420-022-00887-9/MediaObjects/41420_2022_887_Fig1_HTML.png)
NVP-AUY922 alleviates radiation-induced lung injury via inhibition of autophagy-dependent ferroptosis | Cell Death Discovery
![Frontiers | Complex Crystal Structure Determination of Hsp90N-NVP-AUY922 and In Vitro Anti-NSCLC Activity of NVP-AUY922 Frontiers | Complex Crystal Structure Determination of Hsp90N-NVP-AUY922 and In Vitro Anti-NSCLC Activity of NVP-AUY922](https://www.frontiersin.org/files/MyHome%20Article%20Library/847556/847556_Thumb_400.jpg)
Frontiers | Complex Crystal Structure Determination of Hsp90N-NVP-AUY922 and In Vitro Anti-NSCLC Activity of NVP-AUY922
![In vitro sensitivity to NVP-AUY922. Forty-one cell lines with IC50 (A)... | Download Scientific Diagram In vitro sensitivity to NVP-AUY922. Forty-one cell lines with IC50 (A)... | Download Scientific Diagram](https://www.researchgate.net/profile/Habib-Hamidi/publication/236047778/figure/fig4/AS:668497612914699@1536393659774/In-vitro-sensitivity-to-NVP-AUY922-Forty-one-cell-lines-with-IC50-A-represented-in.png)
In vitro sensitivity to NVP-AUY922. Forty-one cell lines with IC50 (A)... | Download Scientific Diagram
![Phase 1/1B trial of the heat shock protein 90 inhibitor NVP‐AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma - Seggewiss‐Bernhardt - 2015 - Cancer - Phase 1/1B trial of the heat shock protein 90 inhibitor NVP‐AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma - Seggewiss‐Bernhardt - 2015 - Cancer -](https://acsjournals.onlinelibrary.wiley.com/cms/asset/1cc3629f-aa8b-4b63-849b-3bf358ec0df7/cncr29339-fig-0001-m.jpg)
Phase 1/1B trial of the heat shock protein 90 inhibitor NVP‐AUY922 as monotherapy or in combination with bortezomib in patients with relapsed or refractory multiple myeloma - Seggewiss‐Bernhardt - 2015 - Cancer -
![Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer Antiproliferative effect of the HSP90 inhibitor NVP-AUY922 is determined by the expression of PTEN in esophageal cancer](https://www.spandidos-publications.com/article_images/or/29/1/OR-29-01-0045-g03.jpg)